References
Query Results -- Details
MGI Accession ID: MGI:54214
J Number: J:5737
Other Accession IDs:
Title: Sulfhydryl compounds in melanocytes of yellow (Ay/a), nonagouti (a/a), and agouti (A/A) mice.
Authors: Galbraith DB; Patrignani AM
Journal: Genetics
Volume: 84
Issue: 3
Date: 1976 Nov
Year: 1976
Pages: 587-91
Review Status: Peer Reviewed
Abstract:
CLEFFMANN (1953, 1963a,b) has reported that yellow but not black melanocytes of agouti (A/A) rabbits contained reducing sulfhydryl compounds. We have attempted to repeat CLEFFMANN's observations in mouse melanocytes of the lethal yellow (Ay/a), nonagouti (a/a) and agouti (A/A) genotypes. Our results contradict those of CLEFFMANN and reveal that yellow and black melanocytes, regardless of genotype, possess equivalent amounts of histochemically detectable sulfhydryl compounds. These results do not support the hypothesis that agouti-locus genes act by controlling the sulfhydryl metabolism of pigment cells.
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