References
Query Results -- Details
MGI Accession ID: MGI:54075
J Number: J:5598
Other Accession IDs:
Title: Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells.
Authors: Walker DG
Journal: Science
Volume: 190
Issue: 4216
Date: 1975 Nov 21
Year: 1975
Pages: 784-5
Review Status: Peer Reviewed
Abstract:
Capacity to resorb bone and calcified cartilage was restored permanently in mice with inherited osteopetrosis by the intravenous administration of cell suspensions prepared from spleen and bone marrow of normal littermates. Beginning near active growth plates as early as 2 weeks after transplantation, replacement of the abnormal spongiosa continued until medullary cavitites were fully expanded.
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