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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm2Tyj
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 2, Tyler Jacks
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MGI ID: |
MGI:3818723 |
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Synonyms: |
R26LSL-LSIY |
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Gene:
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Gt(ROSA)26Sor
Location:
unknown
Genetic Position: Chr6,
48.7 cM
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Mutation
origin |
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Germline Transmission:
| Earliest citation of germline transmission:
J:141383
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: |
Targeted (knock-in) |
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Mutation: |
Insertion |
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A cassette containing a floxed STOP followed by a luciferase gene and sequence encoding the antigen SIYRYYGL (SIY) was inserted into the locus. Cre-mediated recombination is necessary to allow for expression of SIYRYYGL. (J:141383) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| References |
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Original: |
J:141383
Cheung AF et al.,
"Regulated expression of a tumor-associated antigen reveals multiple levels of T-cell tolerance in a mouse model of lung cancer."
Cancer Res 2008 Nov 15;68(22):9459-68
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All: |
1 reference(s)
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