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Ednrbtm1Nrd
Targeted Allele Detail

Nomenclature
Symbol: Ednrbtm1Nrd
Name: endothelin receptor type B; targeted mutation 1, Noah Druckenbrod
MGI ID: MGI:3813973
Synonyms: Ednrbflex3
Gene: Ednrb   Location: Chr14:104213843-104242913 bp, - strand    Genetic Position: Chr14, 51.0 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:140320
Parent Cell Line: R1 (ES Cell)
Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type: Targeted (Floxed/Frt)
Mutation: Insertion
  A floxed neo cassette was placed upstream of exon 3 and an additional loxP site was inserted downstream of exon 3. (J:140320)
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ednrb Mutation: 57 strains or lines available
Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms

(show or hide all annotated terms)

Genotypes are listed in the next section.

      Key:  
hm homozygous ht heterozygous
cn conditional genotype  cx complex: > 1 genome feature
tg involves transgenes ot other: hemizygous, indeterminate,...
N normal phenotype expected model not found
Affected SystemsGenotypes:
 
cn1
  
digestive/alimentary system          
  
embryogenesis          
  
growth/size          
  
life span/aging          
  
pigmentation          
  
skin/coat/nails          
Phenotypic
data by
genotype
Phenotypic Data by Genotype

(show or hide all phenotypic details)

GenotypeAllelic CompositionGenetic Background
  
 cn1   
Ednrbtm1Nrd/Ednrbtm1Nrd
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J
References
Original: J:140320 Druckenbrod NR et al., "Targeting of endothelin receptor-B to the neural crest." Genesis 2008 Aug;46(8):396-400
All: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/20/2009
MGI_4.31
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