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| Nomenclature |
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Symbol:
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Tg(THY1-SNCA*A53T)F53Sud
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Name:
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transgenic insertion F53, Thomas C Sudhof
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MGI ID: |
MGI:3811331 |
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Synonyms: |
F53 |
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Transgene:
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Tg(THY1-SNCA*A53T)F53Sud
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: |
Transgenic (random, expressed) |
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Mutation: |
Insertion |
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The transgenic construct carries the A53T mutant form of the human SNCA (synuclein, alpha) gene under the control of a human THY1 (thymus cell antigen 1, theta) promoter. Expression of the transgene is 10-fold increased in the brain and 20-fold in the spinal cord. (J:140019) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| References |
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Original: |
J:140019
Sudhof TC,
"Generation of a mutant A53T human alpha-synuclein transgene"
MGI Direct Data Submission 2008;():
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All: |
1 reference(s)
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