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| Nomenclature |
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Symbol:
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Tg(tetO-Clock)1Jt
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Name:
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transgene insertion 1, Joseph S Takahashi
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MGI ID: |
MGI:3772938 |
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Synonyms: |
tetO::Clockwt, Tg(tetO-Clock)isoJt |
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Transgene:
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Tg(tetO-Clock)1Jt
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: |
Transgenic (random, expressed) |
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Mutation: |
Insertion |
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A transgenic vector was designed to carry the full-length wildtype mouse Clock gene downstream of a tetracycline-responsive promoter (TRE; tetO). Crossing these mice with mice expressing the tTA or reverse tetracycline-controlled transactivator protein under control of tissue-specific promoters, transgene expression can be regulated in appropriate tissues in the offspring with administration of the tet analog doxycycline.
(J:120326) |
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| References |
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Original: |
J:120326
Hong HK et al.,
"Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior."
PLoS Genet 2007 Feb 23;3(2):e33
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All: |
1 reference(s)
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