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Sorl1Gt(Ex255)Byg
Gene trapped Allele Detail

Nomenclature
Symbol: Sorl1Gt(Ex255)Byg
Name: sortilin-related receptor, LDLR class A repeats-containing; gene trap Ex255, BayGenomics
MGI ID: MGI:3759785
Synonyms: LR-11, Sorl1Gt(pGT1tfr)1Ucd
Gene: Sorl1   Location: Chr9:41772803-41932380 bp, - strand    Genetic Position: Chr9, cytoband B
Mutation
origin
Mutant Cell Line: Ex255 (BayGenomics)
Germline Transmission: Earliest citation of germline transmission: J:125747
Parent Cell Line: Other (see notes) (ES Cell)
Strain of Origin: 129P2/OlaHsd
Mutation
description
Allele Type:   Gene trapped
Mutation:   Insertion of gene trap vector    Vector: pGT1tfr    Vector Type: gene trap
   A gene trap vector, pGT1tfr, was electroporated into 129P2/OlaHsd derived embryonic stem (ES) cells. (J:125747)
Sequence Tags:
Sequence tag details (1 tag)
Genome Context:
Genome Browser view of this mutation
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Sorl1 Mutation: 2 strains or lines available
Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms

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Genotypes are listed in the next section.

      Key:  
hm homozygous ht heterozygous
cn conditional genotype  cx complex: > 1 genome feature
tg involves transgenes ot other: hemizygous, indeterminate,...
N normal phenotype expected model not found
Affected SystemsGenotypes:
 
hm1
  
nervous system          
  
other phenotype          
Phenotypic
data by
genotype
Phenotypic Data by Genotype

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GenotypeAllelic CompositionGenetic Background
  
 hm1   
Sorl1Gt(Ex255)Byg/Sorl1Gt(Ex255)Byg B6.129P2-Sorl1Gt(Ex255)Byg
Notes All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References
Original: J:125747 Hui D et al., "Generation and description of gene trap mutation of Sorl1" MGI Direct Data Submission 2007;():
All: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/20/2009
MGI_4.31
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