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| Nomenclature |
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Symbol:
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Tg(Alb-F5)2Dgi
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Name:
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transgene insertion 2, David Ginsburg
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MGI ID: |
MGI:3709371 |
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Synonyms: |
AlbfvC |
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Transgene:
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Tg(Alb-F5)2Dgi
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x SJL)F1 or C57BL/6 x (C57BL/6 x SJL)F1
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Transgene
description |
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Transgene
Type: |
Transgenic (random, expressed) |
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Mutation: |
Insertion |
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The transgenic construct has the mouse albumin promoter driving expression of the murine F5 (FV) gene including the entire coding sequence. An IRES-EGFP cassette with a bacterial gene wasinserting after the F5 coding sequence. A chimeric intron with optimized splice signals was introduced upstream of the F5 cDNA enhance gene expression. Transgenic F5 expression is restricted to the liver. EGFP expression is not detected.
(J:86150) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:86150
Sun H et al.,
"The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis."
Blood 2003 Oct 15;102(8):2856-61
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All: |
1 reference(s)
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