|
|
| Nomenclature |
|
Symbol:
|
Gt(ROSA)26Sortm1(cre/ESR1)Tyj
|
|
Name:
|
gene trap ROSA 26, Philippe Soriano;
targeted mutation 1, Tyler Jacks
|
|
MGI ID: |
MGI:3699244 |
|
Synonyms: |
R26-Cre-ERT2 |
|
Gene:
|
Gt(ROSA)26Sor
Location:
unknown
Genetic Position: Chr6,
48.7 cM
|
|
Mutation
origin |
|
Germline Transmission:
| Earliest citation of germline transmission:
J:118233
|
|
Parent Cell Line:
| J1 (ES Cell) |
|
Strain of Origin:
|
129S4/SvJae
|
|
Mutation
description |
|
Allele
Type: |
Targeted (knock-in) |
|
Mutation: |
Insertion |
| |
A cassette containing Cre-ERT2 was inserted into the locus. (J:118233) |
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Recombinase specificity
|
|
Driver:
|
Gt(ROSA)26Sor
Summary of all recombinase alleles
driven by Gt(ROSA)26Sor.
|
|
MGI has not yet included tissue specificity data for this allele in any anatomical systems.
|
|
Phenotype
summary
|
|
Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
|
Key:
|
| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
|
|
|
|
|
Phenotypic
data by
genotype
|
|
Phenotypic Data by Genotype
(show or
hide all phenotypic details)
|
|
|
|
| References |
|
Original: |
J:118233
Ventura A et al.,
"Restoration of p53 function leads to tumour regression in vivo."
Nature 2007 Feb 8;445(7128):661-5
|
|
All: |
3 reference(s)
|
|
