|
|
| Nomenclature |
|
Symbol:
|
Apba1tm1Sud
|
|
Name:
|
amyloid beta (A4) precursor protein binding, family A, member 1;
targeted mutation 1, Thomas C Sudhof
|
|
MGI ID: |
MGI:3697697 |
|
Gene:
|
Apba1
Location:
Chr19:23833366-24024087 bp, + strand
Genetic Position: Chr19,
Syntenic
|
|
Mutation
origin |
|
Germline Transmission:
| Earliest citation of germline transmission:
J:81845
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation
description |
|
Allele
Type: |
Targeted (Floxed/Frt) |
|
Mutation: |
Insertion |
| |
Flanking loxP sites were introduced to exon 1 and an frt-flanked neomycin resistance cassette was inserted into the downstream intron via homologous recombination. (J:81845) |
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Phenotypic
data by
genotype
|
|
Phenotypic Data by Genotype
(show or
hide all phenotypic details)
|
| Genotype | Allelic Composition | Genetic Background |
|
  hm1
|
Apba1tm1Sud/Apba1tm1Sud |
involves: 129S1/Sv * 129X1/SvJ |
phenotype not analyzed |
|
|
| References |
|
Original: |
J:81845
Ho A et al.,
"A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission."
Proc Natl Acad Sci U S A 2003 Feb 4;100(3):1409-14
|
|
All: |
3 reference(s)
|
|
