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| Nomenclature |
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Symbol:
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Tg(Prnp-APP)A-2Dbo
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Name:
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transgene insertion A-2, David R Borchelt
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MGI ID: |
MGI:3696803 |
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Transgene:
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Tg(Prnp-APP)A-2Dbo
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: |
Transgenic (random, expressed) |
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Mutation: |
Insertion |
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Mice with this transgene express the human amyloid precursor protein (APP) under control of the mouse prion protein promoter. (J:117538) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
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  tg1
Disease Model |
Tg(Prnp-APP)A-2Dbo/0 |
B6.Cg-Tg(Prnp-APP)A-2Dbo/J |
normal phenotype 1Models involving transgenes or other mutation types may also appear in other sections of the table.
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Disease
models
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1Models involving transgenes or other mutation types may also appear in other sections of the table.
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| References |
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Original: |
J:117538
Borchelt DR,
"Transgenic mice expressing human amyloid precursor protein under the control of the mouse prion protein promoter"
MGI Direct Data Submission 2007;():
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All: |
1 reference(s)
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