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| Nomenclature |
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Symbol:
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Tg(Camk2a-Prkaca)426Tabe
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Name:
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transgene insertion 426, Ted Abel
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MGI ID: |
MGI:3626071 |
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Synonyms: |
CaMKII-R(AB), R(AB), R(AB)-2 |
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Transgene:
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Tg(Camk2a-Prkaca)426Tabe
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6J x CBA/J)F2
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Transgene
description |
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Transgene
Type: |
Transgenic (random, expressed) |
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Mutation: |
Insertion |
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The cAMP-dependent protein kinase A (PKA or PRKACA) RIalpha regulatory subunit, R(AB), was mutated at both cAMP binding sites and placed under control of the mouse Camk2a promoter. (J:38837) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
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  tg1
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Tg(Camk2a-Prkaca)426Tabe/0 |
involves: C57BL/6J * CBA/J |
homeostasis/metabolism behavior/neurological nervous system |
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| References |
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Original: |
J:38837
Abel T et al.,
"Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory."
Cell 1997 Mar 7;88(5):615-26
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All: |
10 reference(s)
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