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Acaa1b Gene Detail
 Symbol
Name
ID
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
MGI:3605455

Nomenclature History
Synonyms thiolase B
Genetic Map
Chromosome 9
Syntenic
 
Mapping data( 1)
Sequence Map
Chr9:119057141-119066211 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
Protein SuperFamily: acetyl-CoA acetyltransferase
TreeFam: TF332308
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000033525 VEGA Gene Model | MGI Sequence Detail 9071 C57BL/6J ± Kb
transcript NM_146230 RefSeq | MGI Sequence Detail 1669 C57BL/6
polypeptide NP_666342 RefSeq | MGI Sequence Detail 424 C57BL/6
For the selected sequences
All sequences(12)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Mice homozygous for a disruption in this gene appear normal.
Polymorphisms SNPs within 2kb(7 from dbSNP Build 128)   SNPs within 2kb including multiple locations(19)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process biological_process
Component mitochondrion
Function acyltransferase activity, transferase activity...
Expression Literature Summary: (1 records)
cDNA source data(129)
External Resources: GEO  ArrayExpress 
Molecular
reagents 		All nucleic(129) cDNA(129)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000010651
Consensus CDS Project CCDS23608.1
UniGene 379402
NIA Mouse Gene Index U031422
Entrez Gene 235674
VEGA Gene Model OTTMUSG00000033525
International Mouse Knockout Project Status Acaa1b
Protein
domains
InterPro ID Description
IPR002155 Thiolase
IPR016038 Thiolase-like, subgroup
IPR016039 Thiolase-like
IPR020610 Thiolase, active site
IPR020613 Thiolase, conserved site
IPR020615 Thiolase, acyl-enzyme intermediate active site
IPR020616 Thiolase, N-terminal
IPR020617 Thiolase, C-terminal
References
(Earliest) J:105494 Chevillard G et al., "Targeted disruption of the peroxisomal thiolase B gene in mouse: a new model to study disorders related to peroxisomal lipid metabolism." Biochimie 2004 Nov;86(11):849-56
(Latest) J:148410 Combes AN et al., "Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development." Dev Dyn 2009 May;238(5):1033-41
All references(3)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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