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| Nomenclature |
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Symbol:
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Tg(Cryaa-TAg)1Ove
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Name:
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transgene insertion 1, Paul Overbeek
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MGI ID: |
MGI:3576674 |
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Synonyms: |
GR19 |
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Transgene:
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Tg(Cryaa-TAg)1Ove
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: |
Transgenic (random, expressed) |
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Mutation: |
Insertion |
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This transgene expresses a truncated form of the SV40 large T antigen under the control of the mouse Cryaa promoter. This promoter is lens-specific. (J:97926) |
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Inheritance: |
Dominant |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
|
  tg1
Disease Model |
Tg(Cryaa-TAg)1Ove/0
Tg(Ins2-CALM1)26Ove/0 |
FVB/N |
homeostasis/metabolism renal/urinary system digestive/alimentary system endocrine/exocrine glands 1Models involving transgenes or other mutation types may also appear in other sections of the table.
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Disease
models
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1Models involving transgenes or other mutation types may also appear in other sections of the table.
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Notes |
Cataracts induced by the expression of this transgene have been used as an obvious visible marker for the presence of coinjected transgenes.
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| References |
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Original: |
J:97926
Epstein PN et al.,
"Calmodulin-induced early-onset diabetes in transgenic mice."
Cell 1989 Sep 22;58(6):1067-73
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All: |
1 reference(s)
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