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| Nomenclature |
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Symbol:
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T(16;17)43H
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Name:
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reciprocal translocation, Chr 16 and 17, Harwell 43
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MGI ID: |
MGI:3574967 |
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Synonyms: |
T43, Ts43H |
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Gene:
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T(16;17)43H
Location:
unknown
Genetic Position: Chr16,
cytoband A
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Mutation
origin |
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Strain of Origin:
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(C3H/HeH x 101/H)F1
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Mutation
description |
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Allele
Type: |
Radiation induced |
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Mutation: |
Translocation |
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This chromosome is a result of a reciprocal translocation with one breakpoint located within the centromeric heterochromatin of Chr16, and the other located in the B3 band of Chr17. In conjunction with a normal Chr16 and two normal Chr17s, the presence of this mutation results in segmental trisomy of the proximal 30 Mb of Chr17, which includes over 310 known genes, and monosomy for the tip of centromeric heterochromatin of Chr16. (J:97039) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
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  ot1
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T(16;17)43H/0 |
101 * C3H * PWD/Ph |
behavior/neurological |
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| References |
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Original: |
J:34742
Lyon MF,
"Autosomal translocations causing male sterility and viable aneuploidy in the mouse"
Cytogenetics 1966;5():335-54
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All: |
3 reference(s)
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