|
|
| Nomenclature |
|
Symbol:
|
Sncbtm1.1Sud
|
|
Name:
|
synuclein, beta;
targeted mutation 1.1, Thomas C Sudhof
|
|
MGI ID: |
MGI:3487297 |
|
Synonyms: |
beta-, BSR |
|
Gene:
|
Sncb
Location:
Chr13:54860221-54867956 bp, - strand
Genetic Position: Chr13,
35.0 cM
|
|
Mutation
origin |
|
Germline Transmission:
| Earliest citation of germline transmission:
J:93544
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation
description |
|
Allele
Type: |
Targeted (knock-out) |
|
Mutation: |
Intragenic deletion |
| |
Sncbtm1Sud mice were crossed with mice expressing cre in the germline, thereby removing floxed exon 2, which encodes amino acids 1-41. (J:93544) |
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Phenotype
summary
|
|
Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
|
Key:
|
| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
|
|
|
|
|
Phenotypic
data by
genotype
|
|
Phenotypic Data by Genotype
(show or
hide all phenotypic details)
|
|
|
|
| References |
|
Original: |
J:93544
Chandra S et al.,
"Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions."
Proc Natl Acad Sci U S A 2004 Oct 12;101(41):14966-71
|
|
All: |
2 reference(s)
|
|
