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| Nomenclature |
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Symbol:
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Sncbtm1Sud
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Name:
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synuclein, beta;
targeted mutation 1, Thomas C Sudhof
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MGI ID: |
MGI:3487296 |
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Synonyms: |
BSF |
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Gene:
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Sncb
Location:
Chr13:54860221-54867956 bp, - strand
Genetic Position: Chr13,
35.0 cM
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Mutation
origin |
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Germline Transmission:
| Earliest citation of germline transmission:
J:93544
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: |
Targeted (Floxed/Frt) |
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Mutation: |
Insertion |
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A targeting vector was designed to flank the first coding exon (exon 2) with loxP sites and to insert an FRT-flanked neomycin resistance gene into intron 3. Crossing with mice expressing FLP recombinase excised the neo. (J:93544) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
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  hm1
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Sncbtm1Sud/Sncbtm1Sud |
involves: 129S1/Sv * 129X1/SvJ |
phenotype not analyzed |
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| References |
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Original: |
J:93544
Chandra S et al.,
"Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions."
Proc Natl Acad Sci U S A 2004 Oct 12;101(41):14966-71
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All: |
1 reference(s)
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