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Tg(tetL)1Bjd
Transgene Detail

Nomenclature
Symbol: Tg(tetL)1Bjd
Name: transgene insertion 1, Hermann Bujard
MGI ID: MGI:3056776
Synonyms: Tg(tetL)1Uh
Transgene: Tg(tetL)1Bjd   Location: unknown    
Transgene
origin
Strain of Origin: NMRI
Transgene
description
Transgene Type: Transgenic (Reporter)
Mutation: Insertion
  The transgene carries the luciferase gene coupled to a tetracycline-responsive promoter element (TRE). (J:93000)
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes Transgenic mice are viable, fertile, and do not display an overt phenotype.

In conjunction with a second transgene expressing the tetracycline-controlled activator proteins tTA or rtTA coupled to a tissue-specific promoter (examples include: Tg(Camk2a-tTA)1Mmay, Tg(Myh6-tTA)6Smbf, and Tg(Nes-rtTA)306Rvs), transgenic mice express luciferase in the appropiate tissue in a tetracycline-inducible fashion.

References
Original: J:93000 Kistner A et al., "Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice." Proc Natl Acad Sci U S A 1996 Oct 1;93(20):10933-8
All: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/20/2009
MGI_4.31
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