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| Nomenclature |
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Symbol:
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Tg(Amy1TAg)354Knw
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Name:
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transgene insertion 354, Barbara Knowles
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MGI ID: |
MGI:3056366 |
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Synonyms: |
354 |
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Transgene:
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Tg(Amy1TAg)354Knw
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6J
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Transgene
description |
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Transgene
Type: |
Transgenic (random, expressed) |
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Mutation: |
Insertion |
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The transgene encodes an amylase 1 (salivary)-SV40 T-antigen hybrid protein and is expressed in the liver. Transgene expression is controlled by the mouse amylase 1, salivary, gene (Amy1) liver isoform promoter. Line 501 was also produced. (J:90326) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
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  tg1
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Tg(Amy1TAg)354Knw/0 |
C57BL/6J-Tg(Amy1TAg)354Knw |
tumorigenesis |
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| References |
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Original: |
J:90326
Fox N et al.,
"Metastatic hibernomas in transgenic mice expressing an alpha-amylase-SV40 T antigen hybrid gene."
Science 1989 Apr 28;244(4903):460-3
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All: |
1 reference(s)
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