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| Nomenclature |
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Symbol:
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Olfr151tm8Mom
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Name:
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olfactory receptor 151;
targeted mutation 8, Peter Mombaerts
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MGI ID: |
MGI:3045146 |
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Synonyms: |
Hyb H, M71-M72 hybrid H |
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Gene:
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Olfr151
Location:
Chr9:37537638-37538566 bp, - strand
Genetic Position: Chr9,
Syntenic
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Mutation
origin |
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Germline Transmission:
| Earliest citation of germline transmission:
J:90716
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: |
Targeted (knock-in) |
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Mutation: |
Insertion |
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Two bp changes resulting in 2 amino acid substitutions (A157T, G161S) and an IRES-tauGFP gene were introduced via homologous recombination. The resulting protein is a hybrid between Olfr151 and Olfr160 which have a total of 25 bp and 11 amino acid differences. The GFP gene was fused after the stop codon and co-expressed with the mutant protein. (J:90716) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| References |
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Original: |
J:90716
Feinstein P et al.,
"A contextual model for axonal sorting into glomeruli in the mouse olfactory system."
Cell 2004 Jun 11;117(6):817-31
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All: |
1 reference(s)
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