Tg(Alb1-Ren)1Unc Other Genome Feature Detail
Symbol
Name
ID
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Tg(Alb1-Ren)1Unc
transgene insertion 1, University of North Carolina
MGI:3039450
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Nomenclature History
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Genetic Map
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Alleles
and
phenotypes
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All alleles(1) :
Targeted, other(1)
| Mice carrying this transgene have hypertension with pathological changes in the kidney and cardiac hypertrophy. |
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References
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(Earliest)
J:89252
Caron KM et al.,
"A genetically clamped renin transgene for the induction of hypertension."
Proc Natl Acad Sci U S A 2002 Jun 11;99(12):8248-52
(Latest)
J:152459
Huby AC et al.,
"Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin."
PLoS One 2009;4(8):e6721
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All references(6)
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