|
|
| Nomenclature |
|
Symbol:
|
Tg(Alb1-Ren)1Unc
|
|
Name:
|
transgene insertion 1, University of North Carolina
|
|
MGI ID: |
MGI:3039271 |
|
Synonyms: |
RenTg, RenTgMK, Tg(Alb1-Ren)1Smi |
|
Gene:
|
Tg(Alb1-Ren)1Unc
Location:
unknown
|
|
Mutation
origin |
|
Germline Transmission:
| Earliest citation of germline transmission:
J:89252
|
|
Parent Cell Line:
| TC-1 (ES Cell) |
|
Strain of Origin:
|
129S6/SvEvTac
|
|
Mutation
description |
|
Allele
Type: |
Targeted (other) |
|
Mutation: |
Insertion |
| |
A single copy of a transgene consisting of a liver specific albumin promoter, a 20 bp insert in the 5' UTR to increase length, a synthetic mouse renin cDNA, and a rabbit beta-globin 3' UTR was inserted into the apolipoprotein locus between the Apoa1 and Apoc3 genes. (J:89252) |
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Phenotype
summary
|
|
Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
|
Key:
|
| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
|
|
|
|
|
Phenotypic
data by
genotype
|
|
Phenotypic Data by Genotype
(show or
hide all phenotypic details)
|
|
|
|
| References |
|
Original: |
J:89252
Caron KM et al.,
"A genetically clamped renin transgene for the induction of hypertension."
Proc Natl Acad Sci U S A 2002 Jun 11;99(12):8248-52
|
|
All: |
6 reference(s)
|
|
