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Disc1 Gene Detail
 Symbol
Name
ID
Disc1
disrupted in schizophrenia 1
MGI:2447658

Nomenclature History
Genetic Map
Chromosome 8
69.6 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 1)

Sequence Map
Chr8:127578095-127785758 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Disc1 ± 2 cM)
TreeFam: TF332357
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000032471 VEGA Gene Model | MGI Sequence Detail 207664 C57BL/6J ± Kb
transcript NM_174854 RefSeq | MGI Sequence Detail 2597 C57BL/6
polypeptide Q811T9 UniProt | EBI | MGI Sequence Detail 852 Not Applicable
For the selected sequences
All sequences(23)
Alleles
and
phenotypes 		All alleles(4) : Targeted, knock-out(1) Spontaneous(1) Chemically induced(2)
Associated Human Diseases (2)   Alleles Annotated to Human Diseases (3)  
Polymorphisms SNPs within 2kb(1221 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(5)
Process biological_process
Component cytoplasm, cytoskeleton...
Function protein binding
External Resources: MouseFunc
Expression Literature Summary: (6 records)
Data Summary: Assays (1)    Results (99)    Tissues (32)
Theiler Stages: 22,24,26,28
  Assay Type Assays   Results
      RNA in situ 1   99
cDNA source data(3)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(6) Genomic(3) cDNA(3)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000043051
DoTS DT.101368711, DT.101368712, DT.101368713, DT.101724222
UniGene 233504
DFCI TC1591950, TC1727875
NIA Mouse Gene Index U040714, U380271
Entrez Gene 244667
VEGA Gene Model OTTMUSG00000032471
International Mouse Knockout Project Status Disc1
References
(Earliest) J:80804 Ma L et al., "Cloning and Characterization of Disc1, the Mouse Ortholog of DISC1 (Disrupted-in-Schizophrenia 1)." Genomics 2002 Dec;80(6):662-72
(Latest) J:151421 Meyer KD et al., "Disc1 regulates granule cell migration in the developing hippocampus." Hum Mol Genet 2009 Sep 1;18(17):3286-97
All references(17)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
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