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| Nomenclature |
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Symbol:
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Tg(Tagln-tTA)1Mrab
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Name:
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transgene insertion 1, Marlene Rabinovitch
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MGI ID: |
MGI:2447082 |
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Synonyms: |
SM22alpha- tTA, tTA+ |
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Transgene:
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Tg(Tagln-tTA)1Mrab
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: |
Transgenic (random, expressed) |
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Mutation: |
Insertion |
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Sequence encoding a tetracycline transactivator was adjoined to the smooth muscle cell specific transgelin promoter. The promoter was reported to drive expression in the aorta, but not in the heart, lung, kidney, bladder, intestine, or stomach. (J:70031) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| References |
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Original: |
J:70031
Ju H et al.,
"Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice."
Proc Natl Acad Sci U S A 2001 Jun 19;98(13):7469-74
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All: |
3 reference(s)
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