About   Help   FAQ
Tour our new Quick Search
Malt1 Gene Detail
 Symbol
Name
ID
Malt1
mucosa associated lymphoid tissue lymphoma translocation gene 1
MGI:2445027

Nomenclature History
Synonyms D430033E09Rik, paracaspase
Genetic Map
Chromosome 18
Syntenic
 
Mapping data( 1)
Sequence Map
Chr18:65590617-65638477 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: mucosa-associated lymphoid tissue lymphoma translocation protein 1
TreeFam: TF319744
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000014910 VEGA Gene Model | MGI Sequence Detail 47861 C57BL/6J ± Kb
transcript NM_172833 RefSeq | MGI Sequence Detail 5008 C57BL/6
polypeptide Q2TBA3 UniProt | EBI | MGI Sequence Detail 832 Not Applicable
For the selected sequences
All sequences(25)
Alleles
and
phenotypes 		All alleles(5) : Targeted, knock-out(2) Gene trapped(3)
Polymorphisms SNPs within 2kb(192 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process apoptosis, B cell activation...
Component cytoplasm, cytosol...
Function cysteine-type endopeptidase activity, hydrolase activity...
External Resources: FuncBase
Expression cDNA source data(42)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(42) cDNA(42)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000032688
DoTS DT.103565927, DT.60100513, DT.91317063, DT.91581418, DT.91598033
Consensus CDS Project CCDS29306.1
UniGene 132613
DFCI TC1580837, TC1596346, TC1644537
NIA Mouse Gene Index U018825
Entrez Gene 240354
VEGA Gene Model OTTMUSG00000014910
International Mouse Knockout Project Status Malt1
Protein
domains
InterPro ID Description
IPR001309 Peptidase C14, ICE, catalytic subunit p20
IPR003598 Immunoglobulin subtype 2
IPR007110 Immunoglobulin-like
IPR011029 DEATH-like
IPR011600 Peptidase C14, caspase catalytic
IPR013098 Immunoglobulin I-set
IPR013783 Immunoglobulin-like fold
Graphical View of Protein Domain Structure
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs" Nature 2002;420():563-573
(Latest) J:155688 Tusche MW et al., "Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets." J Exp Med 2009 Nov 23;206(12):2671-83
All references(18)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory