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Ppp2r2c Gene Detail
 Symbol
Name
ID
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
MGI:2442660


Nomenclature History
Synonyms 6330548O06Rik, IMYPNO1, PR52
Genetic Map
Chromosome 5
Syntenic
 
Mapping data( 1)
Sequence Map
Chr5:37259752-37346317 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: serine/threonine-protein phosphatase 2A, subunit B55
TreeFam: TF105553
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000022772 VEGA Gene Model | MGI Sequence Detail 86566 C57BL/6J ± Kb
transcript NM_172994 RefSeq | MGI Sequence Detail 4066 C57BL/6
polypeptide Q8BG02 UniProt | EBI | MGI Sequence Detail 447 Not Applicable
For the selected sequences
All sequences(17)
Alleles
and
phenotypes
All alleles(1) : Gene trapped(1)
Polymorphisms SNPs within 2kb(474 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process signal transduction
Component protein phosphatase type 2A complex
Function protein phosphatase type 2A regulator activity
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (1)    Results (4)    Tissues (2)    Images (1)
Theiler Stages: 4,5
  Assay Type Assays   Results
      RT-PCR 1   4
cDNA source data(33)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(34) cDNA(33) Primer pair(1)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000029120
DoTS DT.40137680
Consensus CDS Project CCDS19244.1
UniGene 41694
DFCI TC1577799
NIA Mouse Gene Index U005517
Entrez Gene 269643
VEGA Gene Model OTTMUSG00000022772
International Mouse Knockout Project Status Ppp2r2c
Protein
domains
InterPro ID Description
IPR000009 Protein phosphatase 2A, regulatory subunit PR55
IPR001680 WD40 repeat
IPR011046 WD40 repeat-like-containing domain
IPR015943 WD40/YVTN repeat-like-containing domain
IPR018067 Protein phosphatase 2A, regulatory subunit PR55, conserved site
IPR019781 WD40 repeat, subgroup
Graphical View of Protein Domain Structure
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs" Nature 2002;420():563-573
(Latest) J:153617 O'Shaughnessy RF et al., "Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development." Development 2009 Oct;136(20):3423-31
All references(3)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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