|
|
| Nomenclature |
|
Symbol:
|
Gt(ROSA)26Sortm1(FLP1)Dym
|
|
Name:
|
gene trap ROSA 26, Philippe Soriano;
targeted mutation 1, Susan Dymecki
|
|
MGI ID: |
MGI:2429412 |
|
Synonyms: |
CAGGS-Flpe, flipper, FLP, FLP deleter, FLPe, FLPeR, R26Fki, ROSA26::FLPe knock in |
|
Gene:
|
Gt(ROSA)26Sor
Location:
unknown
Genetic Position: Chr6,
48.7 cM
|
|
Mutation
origin |
|
Germline Transmission:
| Earliest citation of germline transmission:
J:66893
|
|
Parent Cell Line:
| AK7 (ES Cell) |
|
Strain of Origin:
|
129S4/SvJaeSor
|
|
Mutation
description |
|
Allele
Type: |
Targeted (knock-in) |
|
Mutation: |
Insertion |
| |
An enhanced flp cassette containing a splice acceptor site was ligated to a downstream PGK-neo cassette and inserted at the endogenous locus. Efficient frt-specific recombination in transgenic mice carrying a reporter gene was reported to reflect constituitive expression of the Gt(ROSA)26Sor from preimplantation onward. (J:66893, J:92442) |
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Recombinase specificity
|
|
Driver:
|
Gt(ROSA)26Sor
Summary of all recombinase alleles
driven by Gt(ROSA)26Sor.
|
|
MGI has not yet included tissue specificity data for this allele in any anatomical systems.
|
|
Phenotypic
data by
genotype
|
|
Phenotypic Data by Genotype
(show or
hide all phenotypic details)
|
|
|
|
| References |
|
Original: |
J:66893
Farley FW et al.,
"Widespread recombinase expression using FLPeR (Flipper) mice"
Genesis 2000 Nov-Dec;28(3-4):106-10
|
|
All: |
81 reference(s)
|
|
