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| Nomenclature |
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Symbol:
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Mgat5tm1Jwd
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Name:
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mannoside acetylglucosaminyltransferase 5;
targeted mutation 1, James W Dennis
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MGI ID: |
MGI:2152619 |
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Synonyms: |
Mgat5- |
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Gene:
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Mgat5
Location:
Chr1:129101563-129379549 bp, + strand
Genetic Position: Chr1,
Syntenic
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Mutation
origin |
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Germline Transmission:
| Earliest citation of germline transmission:
J:60960
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: |
Targeted (Reporter) |
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Mutations: |
Insertion, Intragenic deletion |
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A LacZ and neomycin resistance cassette replaced part of exon 1. (J:60960) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
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  hm1
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Mgat5tm1Jwd/Mgat5tm1Jwd |
involves: 129S1/Sv * 129X1/SvJ |
immune system tumorigenesis renal/urinary system behavior/neurological |
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| References |
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Original: |
J:60960
Granovsky M et al.,
"Suppression of tumor growth and metastasis in Mgat5-deficient mice."
Nat Med 2000 Mar;6(3):306-12
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All: |
10 reference(s)
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