Symbol
Name
ID
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Synonyms
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alpha CGRP, CA, Calc, Cgrp, CT, Ct, Ctn
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(28)
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Alleles
and
phenotypes
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All alleles(4) :
Targeted, knock-out(2)
Targeted, other(2)
| Two separate peptides, calcitonin and calcitonin gene related peptide-alpha (CGRP-alpha), are derived from this locus by alternative splicing. Mice homozygous null for CGRP-alpha have changes in the vascular and nervous system. Mice lacking calcitonin have increased bone mineralization. |
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Polymorphisms
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All PCR and RFLP(2) :
PCR(1)
RFLP(1)
SNPs within 2kb(57 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (96 records)
Data Summary:
Assays (5)
Results (18)
Tissues (9)
Images (9)
Theiler Stages: 22,24,26,28
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Assay Type |
Assays |
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Results |
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RNA in situ |
1 |
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1 |
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Immunohistochemistry |
4 |
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17 |
cDNA source data(35)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(38)
cDNA(37)
Primer pair(1)
Antibodies(5)
Microarray probesets(3)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:6525
Jacobs JW et al.,
"Calcitonin messenger RNA encodes multiple polypeptides in a single precursor."
Science 1981 Jul 24;213(4506):457-9
(Latest)
J:154238
Becklund BR et al.,
"The calcitonin/calcitonin gene related peptide-alpha gene is not required for 1alpha,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis."
Arch Biochem Biophys 2009 Aug 15;488(2):105-8
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All references(178)
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Other
accession IDs
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MGD-MRK-1732, MGD-MRK-2210, MGD-MRK-2239, MGI:1101063, MGI:88249
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