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Nkd1 Gene Detail
 Symbol
Name
ID
Nkd1
naked cuticle 1 homolog (Drosophila)
MGI:2135954


Nomenclature History
Synonyms 2810434J10Rik, 9030215G15Rik
Genetic Map
Chromosome 8
cytoband C4
 
Mapping data( 2)
Sequence Map
Chr8:91045269-91116222 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF328786
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000031661 Ensembl Gene Model | MGI Sequence Detail 70954 C57BL/6J ± Kb
transcript NM_027280 RefSeq | MGI Sequence Detail 4314 C57BL/6
polypeptide Q99MH6 UniProt | EBI | MGI Sequence Detail 471 Not Applicable
For the selected sequences
All sequences(32)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Homozygous null mice display reduced male fertility with oligozoospermia, small testis, and small seminiferous tubules.
Polymorphisms SNPs within 2kb(449 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cell differentiation, multicellular organismal development...
Component cytoplasm, membrane...
Function calcium ion binding, protein binding...
External Resources: FuncBase
Expression Literature Summary: (7 records)
Data Summary: Assays (13)    Results (60)    Tissues (28)    Images (39)
Theiler Stages: 17,22,24,26,28
  Assay Type Assays   Results
      Western blot 2   8
      RT-PCR 5   9
      RNA in situ 2   18
      Northern blot 4   25
cDNA source data(8)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(14) cDNA(9) Primer pair(5) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000031661
DoTS DT.101722344, DT.40177224, DT.91570237, DT.97411141
Consensus CDS Project CCDS22511.1
DFCI TC1579018, TC1602640, TC1617928, TC1707740
NIA Mouse Gene Index U009622, U052755
Entrez Gene 93960
International Mouse Knockout Project Status Nkd1
Protein
domains
InterPro ID Description
IPR011992 EF-hand-like domain
IPR018247 EF-Hand 1, calcium-binding site
IPR018249 EF-HAND 2
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:122353 Zhang S et al., "Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2." Mol Cell Biol 2007 Jun;27(12):4454-64
All references(11)
Other
accession IDs
MGI:1917223, MGI:1924913

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory