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Ppp2r1a Gene Detail
 Symbol
Name
ID
Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
MGI:1926334


Nomenclature History
Synonyms 6330556D22Rik, PP2A, PR65, protein phosphatase PP2A
Genetic Map
Chromosome 17
cytoband A3.2
 
Mapping data( 3)
Sequence Map
Chr17:21082275-21102880 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: serine/threonine-protein phosphataser PP2A regulatory subunit A
TreeFam: TF105552
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000016281 VEGA Gene Model | MGI Sequence Detail 20606 C57BL/6J ± Kb
transcript NM_016891 RefSeq | MGI Sequence Detail 2256 C57BL/6
polypeptide Q76MZ3 UniProt | EBI | MGI Sequence Detail 589 Not Applicable
For the selected sequences
All sequences(31)
Alleles
and
phenotypes
All alleles(3) : Gene trapped(3)
Polymorphisms SNPs within 2kb(27 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Component cytosol, protein phosphatase type 2A complex...
Function binding, protein binding...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (4)    Results (17)    Tissues (9)
Theiler Stages: 23,28
  Assay Type Assays   Results
      Western blot 1   4
      RT-PCR 2   8
      Immunohistochemistry 1   5
cDNA source data(525)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(527) cDNA(525) Primer pair(2) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000007564
DoTS DT.55100301, DT.91397660, DT.94251305
Consensus CDS Project CCDS28432.1
UniGene 294138
PDB 2IAE, 2PF4, 3FGA
DFCI TC1573812
Entrez Gene 51792
VEGA Gene Model OTTMUSG00000016281
International Mouse Knockout Project Status Ppp2r1a
Protein
domains
InterPro ID Description
IPR000357 HEAT
IPR011989 Armadillo-like helical
IPR016024 Armadillo-type fold
Graphical View of Protein Domain Structure
References
(Earliest) J:11704 Matsuzawa S et al., "Increase in potential activities of protein phosphatases PP1 and PP2A in lymphoid tissues of autoimmune MRL/MpJ-lpr/lpr mice." J Biochem 1992 Apr;111(4):472-7
(Latest) J:144600 Deng X et al., "Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding." Blood 2009 Jan 8;113(2):422-8
All references(16)
Other
accession IDs
MGI:1923432

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/06/2010
MGI_4.32
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