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Senp2 Gene Detail
 Symbol
Name
ID
Senp2
SUMO/sentrin specific peptidase 2
MGI:1923076

Nomenclature History
Synonyms 2310007L05Rik, 4930538C18Rik, KIAA1331, mKIAA1331, SMT3IP2
Genetic Map
Chromosome 16
cytoband B1
 
Mapping data( 3)
Sequence Map
Chr16:22009582-22047948 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF316289
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000022855 Ensembl Gene Model | MGI Sequence Detail 38367 C57BL/6J ± Kb
transcript NR_027488 RefSeq | MGI Sequence Detail 4566 C57BL/6
polypeptide Q91ZX6 UniProt | EBI | MGI Sequence Detail 588 Not Applicable
For the selected sequences
All sequences(29)
Alleles
and
phenotypes 		All alleles(13) : Targeted, other(1) Gene trapped(12)
Homozygous null mice are embryonic lethal due to placental defects resulting from abnormal trophoblast maturation.
Polymorphisms SNPs within 2kb(150 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process modification-dependent protein catabolic process, mRNA transport...
Component cytoplasm, cytoplasmic vesicle...
Function cysteine-type peptidase activity, hydrolase activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
cDNA source data(6)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(6) cDNA(6)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000022855
DoTS DT.101388976, DT.490379, DT.91379741, DT.97372273
Consensus CDS Project CCDS28065.1
DFCI TC1574782, TC1594824, TC1606389, TC1753192
NIA Mouse Gene Index U043508
Entrez Gene 75826
International Mouse Knockout Project Status Senp2
Protein
domains
InterPro ID Description
IPR003653 Peptidase C48, SUMO/Sentrin/Ubl1
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:144707 Chiu SY et al., "SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages." PLoS Biol 2008 Dec 16;6(12):e310
All references(8)
Other
accession IDs 		MGI:1916738, MGI:2146470, MGI:2146665
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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