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Hyal5 Gene Detail
 Symbol
Name
ID
Hyal5
hyaluronoglucosaminidase 5
MGI:1921718

Nomenclature History
Synonyms 4933439A12Rik
Genetic Map
Chromosome 6
7.3 cM, cytoband A3
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr6:24825943-24841958 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: hyaluronidase
TreeFam: TF321598
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000029678 Ensembl Gene Model | MGI Sequence Detail 16016 C57BL/6J ± Kb
transcript NM_028957 RefSeq | MGI Sequence Detail 2070 C57BL/6
polypeptide NP_083233 RefSeq | MGI Sequence Detail 526 C57BL/6
For the selected sequences
All sequences(14)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(2)
Reproduction is normal in mice with null mutations at this marker.
Polymorphisms SNPs within 2kb(78 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process penetration of zona pellucida
Component acrosomal vesicle, external side of plasma membrane...
Function hyalurononglucosaminidase activity
External Resources: FuncBase
Expression cDNA source data(10)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(10) cDNA(10)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000029678
DoTS DT.55171089
Consensus CDS Project CCDS19948.1
UniGene 251601
DFCI TC1586825
NIA Mouse Gene Index U006601
Entrez Gene 74468
International Mouse Knockout Project Status Hyal5
Protein
domains
InterPro ID Description
IPR001439 Glycoside hydrolase, family 56, sperm surface protein PH20
IPR001968 Glycoside hydrolase, family 56
IPR013785 Aldolase-type TIM barrel
IPR017430 Glycoside hydrolase, family 56, Hyaluronidase
IPR017853 Glycoside hydrolase, catalytic core
IPR018155 Hyaluronidase
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:154516 Kimura M et al., "Functional roles of mouse sperm hyaluronidases, HYAL5 and SPAM1, in fertilization." Biol Reprod 2009 Nov;81(5):939-47
All references(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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