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Nfatc4 Gene Detail
 Symbol
Name
ID
Nfatc4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
MGI:1920431


Nomenclature History
Synonyms 3110041H08Rik
Genetic Map
Chromosome 14
cytoband C1
 
Mapping data( 3)
Sequence Map
Chr14:56443845-56452780 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF326480
Sequences
Representative Sequences Length Strain/Species Flank
genomic 73181 NCBI Gene Model | MGI Sequence Detail 8936 C57BL/6J ± Kb
transcript NM_001168346 RefSeq | MGI Sequence Detail 4036 C57BL/6
polypeptide Q8K120 UniProt | EBI | MGI Sequence Detail 901 Not Applicable
For the selected sequences
All sequences(36)
Alleles
and
phenotypes
All alleles(7) : Targeted, knock-out(2) Gene trapped(5)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms SNPs within 2kb(59 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell differentiation, cellular respiration...
Component cytoplasm, nucleus...
Function DNA binding, transcription factor activity...
External Resources: FuncBase
Expression Literature Summary: (11 records)
Data Summary: Assays (3)    Results (34)    Tissues (34)    Images (4)
Theiler Stages: 17,21,24,28
  Assay Type Assays   Results
      RT-PCR 1   2
      RNA in situ 2   32
cDNA source data(45)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(46) cDNA(45) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000023411
DoTS DT.101407580, DT.99842291, DT.99842293
Consensus CDS Project CCDS27132.1
UniGene 27908
DFCI TC1581336, TC1600964, TC1627487
NIA Mouse Gene Index U015669
Entrez Gene 73181
International Mouse Knockout Project Status Nfatc4
Protein
domains
InterPro ID Description
IPR002909 Cell surface receptor IPT/TIG
IPR008366 Nuclear factor of activated T cells (NFAT)
IPR008967 p53-like transcription factor, DNA-binding
IPR011539 Rel homology
IPR013783 Immunoglobulin-like fold
IPR014756 Immunoglobulin E-set
IPR018286 Nuclear factor of activated T cells (NFAT), subgroup
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:153636 Zeini M et al., "Spatial and temporal regulation of coronary vessel formation by calcineurin-NFAT signaling." Development 2009 Oct;136(19):3335-45
All references(27)
Other
accession IDs
MGI:2145795, MGI:2145827

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
02/06/2010
MGI_4.32
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