Symbol
Name
ID
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Synonyms
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5730488L07Rik, mKIAA1142
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Genetic Map
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Chromosome 7
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Syntenic
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Mapping data(
2)
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(24)
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Alleles and phenotypes
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All alleles(104) :
Targeted, knock-out(2)
Targeted, other(1)
Gene trapped(101)
| Homozygous null mice die at midgestation exhibiting heart defects as well as impaired neuronal development and yolk sac vasculature. |
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Polymorphisms
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SNPs within 2kb(120 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (4 records)
Data Summary:
Assays (2)
Results (96)
Tissues (94)
Images (11)
Theiler Stages: 22,28
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Assay Type |
Assays |
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Results |
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Western blot |
1 |
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3 |
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RNA in situ |
1 |
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93 |
cDNA source data(62)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular reagents
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All nucleic(63)
cDNA(62)
Primer pair(1)
Antibodies(1)
Microarray probesets(1)
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Other database links
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Protein domains
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| InterPro ID |
Description |
| IPR000095 |
PAK-box/P21-Rho-binding |
| IPR000719 |
Protein kinase, catalytic domain |
| IPR002290 |
Serine/threonine-protein kinase domain |
| IPR011009 |
Protein kinase-like domain |
| IPR015750 |
Serine/threonine-protein kinase, Pak-related |
| IPR017441 |
Protein kinase, ATP binding site |
| IPR017442 |
Serine/threonine-protein kinase-like domain |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:65060
Kawai J et al.,
"Functional annotation of a full-length mouse cDNA collection."
Nature 2001 Feb 8;409(6821):685-90
(Latest)
J:152821
Tian Y et al.,
"Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation."
Mech Dev 2009 Aug-Sep;126(8-9):710-20
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All references(12)
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Other accession IDs
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MGI:2142263
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