Symbol
Name
ID
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Synonyms
|
5830451P18Rik, Duplin, mKIAA1564
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Genetic Map
|
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Chromosome 14
|
Syntenic
|
|
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Mapping data(
2)
|
|
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Sequence Map
|
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Mammalian
homology
|
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Sequences
|
All sequences(35)
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Alleles
and
phenotypes
|
All alleles(10) :
Targeted, knock-out(1)
Gene trapped(9)
| Homozygous null embryos are growth retarded starting at E5.5 and exhibit developmental arrest at E6.5. Mutants develop into an egg cylinder but do not form a primitive streak or mesoderm and exhibit increased apoptosis at E7.5. |
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Polymorphisms
|
SNPs within 2kb(146 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (3 records)
cDNA source data(11)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(14)
Genomic(1)
cDNA(13)
Microarray probesets(1)
|
Other database
links
|
| Ensembl Gene Model |
ENSMUSG00000053754 |
| DoTS |
DT.101165083, DT.527046, DT.91335432, DT.94211283, DT.94211287, DT.94211290, DT.94217030 |
| Consensus CDS Project |
CCDS36919.1 |
| DFCI |
TC1576225, TC1605081, TC1608917, TC1616466, TC1695742 |
| NIA Mouse Gene Index |
U035535 |
| Entrez Gene |
67772 |
| VEGA Gene Model |
OTTMUSG00000023392 |
| International Mouse Knockout Project Status |
Chd8 |
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:28401
Bettenhausen B et al.,
"Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos."
Genomics 1995 Aug 10;28(3):436-41
(Latest)
J:146960
Nishiyama M et al.,
"CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis."
Nat Cell Biol 2009 Feb;11(2):172-82
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All references(11)
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Other
accession IDs
|
MGI:2145721, MGI:3510543
|
Analysis Tools
MGI BioMart