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Fzd2 Gene Detail
 Symbol
Name
ID
Fzd2
frizzled homolog 2 (Drosophila)
MGI:1888513

Nomenclature History
Synonyms Fz10, Mfz10, Mfz10a
Genetic Map
Chromosome 11
Syntenic
 
Mapping data( 2)
Sequence Map
Chr11:102465710-102469372 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: G protein-coupled receptor frizzled
TreeFam: TF317907
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000002949 VEGA Gene Model | MGI Sequence Detail 3663 C57BL/6J ± Kb
transcript NM_020510 RefSeq | MGI Sequence Detail 3628 C57BL/6
polypeptide Q9JIP6 UniProt | EBI | MGI Sequence Detail 570 Not Applicable
For the selected sequences
All sequences(28)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(1) Gene trapped(1)
Polymorphisms SNPs within 2kb(18 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cell surface receptor linked signal transduction, cell-cell signaling...
Component integral to membrane, membrane...
Function G-protein coupled receptor activity, non-G-protein coupled 7TM receptor activity...
External Resources: FuncBase
Expression Literature Summary: (27 records)
Data Summary: Assays (7)    Results (208)    Tissues (123)    Images (33)
Theiler Stages: 1,2,3,4,5,19,20,22,23,24,26,28
  Assay Type Assays   Results
      RT-PCR 3   21
      RNA in situ 4   187
cDNA source data(7)
External Resources: GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(12) cDNA(8) Primer pair(4)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000050288
DoTS DT.101296330, DT.524904
Consensus CDS Project CCDS25501.1
DFCI TC1582930, TC1638294, TC1684067
NIA Mouse Gene Index U013394
Entrez Gene 57265
VEGA Gene Model OTTMUSG00000002949
International Mouse Knockout Project Status Fzd2
Protein
domains
InterPro ID Description
IPR000024 Frizzled cysteine-rich domain
IPR000539 Frizzled protein
IPR015526 Frizzled related
IPR017981 GPCR, family 2-like
IPR020067 Frizzled-like domain
IPR020068 Frizzled domain, subgroup
Graphical View of Protein Domain Structure
References
(Earliest) J:37068 Wang Y et al., "A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled." J Biol Chem 1996 Feb 23;271(8):4468-76
(Latest) J:155074 Agalliu D et al., "Motor neurons with axial muscle projections specified by Wnt4/5 signaling." Neuron 2009 Mar 12;61(5):708-20
All references(34)
Other
accession IDs 		MGI:2144531
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory