Hk Spontaneous Allele Detail MGI Mouse (MGI:1861098)

Hk
Spontaneous Allele Detail

Nomenclature

Symbol:	Hk
Name:	hook
MGI ID:	MGI:1861098
Gene:	Hk Location: unknown Genetic Position: Chr8, 26.0 cM

Mutation
origin

Strain of Origin:

piebald shaker stock

Mutation
description

Allele Type:	Spontaneous
Inheritance:	Dominant

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)

Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Hk Mutation:	1 strain or line available

Phenotype
summary

Phenotype Summary by Mammalian Phenotype terms

(show or hide all annotated terms)

Genotypes are listed in the next section.

Key:

hm	homozygous	ht	heterozygous
cn	conditional genotype	cx	complex: > 1 genome feature
tg	involves transgenes	ot	other: hemizygous, indeterminate,...
N	normal phenotype		expected model not found

Affected Systems	Genotypes:	hm1	ht2
digestive/alimentary system		√	√
abnormal anus morphology		√	√
		hm1	ht2
limbs/digits/tail		√	√
abnormal caudal vertebrae morphology		√	√
kinked tail		√	√
short tail		√	√
		hm1	ht2
skeleton		√	√
abnormal caudal vertebrae morphology		√	√

Phenotypic
data by
genotype

Phenotypic Data by Genotype

(show or hide all phenotypic details)

Genotype	Allelic Composition	Genetic Background
hm1	Hk/Hk	Not Specified
digestive/alimentary system abnormal anus morphology (J:14985) limbs/digits/tail abnormal caudal vertebrae morphology (J:14985) kinked tail (J:14985) short tail (J:14985) skeleton abnormal caudal vertebrae morphology (J:14985)
Genotype	Allelic Composition	Genetic Background
ht2	Hk/Hk⁺	Not Specified
digestive/alimentary system abnormal anus morphology (J:14985) the often slit-shaped anus is posterior to normal location, often on the tail, extending sometimes to half the length of the tail mice with this feature may or may not have a short tail or a hook-tail anus tends to be bare rather than surrounded by hair limbs/digits/tail abnormal caudal vertebrae morphology (J:14985) kinked tail (J:14985) end of tail is fishhook-like length and degree of bending is variable short tail (J:14985) this feature is variable skeleton abnormal caudal vertebrae morphology (J:14985)

References

Original:	J:14985 Holman SP, "The hook-tailed mouse" J Hered 1951;42():305-06
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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