Symbol
Name
ID
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Synonyms
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Nik
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(21)
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Alleles
and
phenotypes
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All alleles(4) :
Targeted, knock-out(1)
Gene trapped(1)
Spontaneous(1)
Chemically induced(1)
| Homozygotes for a spontaneous mutation exhibit deficiencies in cellular and humoral immunity, susceptibility to infections, absence of lymph nodes and Peyer's patches, failure of isotype switching, and inflammation of exocrine organs. |
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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SNPs within 2kb(361 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (1 records)
Data Summary:
Assays (1)
Results (93)
Tissues (93)
Images (15)
Theiler Stages: 22
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Assay Type |
Assays |
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Results |
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RNA in situ |
1 |
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93 |
cDNA source data(5)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
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All nucleic(9)
Genomic(1)
cDNA(6)
Primer pair(1)
Other(1)
Microarray probesets(3)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR000719 |
Protein kinase, catalytic domain |
| IPR008271 |
Serine/threonine-protein kinase, active site |
| IPR011009 |
Protein kinase-like domain |
| IPR017425 |
Mitogen-activated protein kinase kinase kinase 14 |
| IPR017441 |
Protein kinase, ATP binding site |
| IPR017442 |
Serine/threonine-protein kinase-like domain |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:16865
Miyawaki S et al.,
"A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice."
Eur J Immunol 1994 Feb;24(2):429-34
(Latest)
J:154064
Nagatake T et al.,
"Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity."
J Exp Med 2009 Oct 26;206(11):2351-64
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All references(87)
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Other
accession IDs
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MGD-MRK-18699, MGI:101874
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Analysis Tools
MGI BioMart
