|
|
| Nomenclature |
|
Symbol:
|
Tgfawa1
|
|
Name:
|
transforming growth factor alpha;
waved 1
|
|
MGI ID: |
MGI:1856388 |
|
Synonyms: |
wa-1, waved |
|
Gene:
|
Tgfa
Location:
Chr6:86145415-86225151 bp, + strand
Genetic Position: Chr6,
35.8 cM
|
|
Mutation
origin |
|
Strain of Origin:
|
Not Specified
|
|
Mutation
description |
|
Allele
Type: |
Spontaneous |
|
Mutation: |
Undefined |
| |
This allele was identified by a noncomplementation test with Tgfatm1Unc. Although the specific molecular lesion has not been identified, Northern blot analysis revealed that expression of TGFalpha transcript was reduced in homozygous mice. (J:4605) |
|
Inheritance: |
Recessive |
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Phenotype
summary
|
|
Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
|
Key:
|
| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
|
|
|
|
|
Phenotypic
data by
genotype
|
|
Phenotypic Data by Genotype
(show or
hide all phenotypic details)
|
| Genotype | Allelic Composition | Genetic Background |
|
  hm1
|
Tgfawa1/Tgfawa1 |
Not Specified |
skin/coat/nails touch/vibrissae vision/eye immune system |
|
|
| References |
|
Original: |
J:13034
Crew FAE,
"Waved: an autosomal recessive coat form character in the mouse."
J Genet 1933;27():95-96
|
|
All: |
15 reference(s)
|
|
