Apc<Min> Chemically induced Allele Detail MGI Mouse (MGI:1856318)

Apc^Min
Chemically induced Allele Detail

Nomenclature

Symbol:	Apc^Min
Name:	adenomatosis polyposis coli; multiple intestinal neoplasia
MGI ID:	MGI:1856318
Synonyms:	Apc^Δ850, Apc^-, Apc^delta850, Min, Min-
Gene:	Apc Location: Chr18:34380638-34479735 bp, + strand Genetic Position: Chr18, 15.0 cM

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:	Chemically induced (ENU)
Mutation:	Single point mutation
	A transversion point mutation that alters nucleotide 2549 from a T to an A. This converts codon 850 from one encoding a leucine to a stop codon. (J:830)
Inheritance:	Dominant

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)

Carrying this Mutation:	Mouse Strains: 5 strains available Cell Lines: 0 lines available
Carrying any Apc Mutation:	46 strains or lines available

Expression

In Mice Carrying this Mutation:

Phenotype
summary

Phenotype Summary by Mammalian Phenotype terms

(show or hide all annotated terms)

Genotypes are listed in the next section.

Key:

hm	homozygous	ht	heterozygous
cn	conditional genotype	cx	complex: > 1 genome feature
tg	involves transgenes	ot	other: hemizygous, indeterminate,...
N	normal phenotype		expected model not found