Symbol
Name
ID
|
|
|
Synonyms
|
dactylin, dactylyn, Fbw4
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(20)
|
Alleles
and
phenotypes
|
All alleles(7) :
Gene trapped(5)
Spontaneous(2)
| Homozygotes for a spontaneous null mutation lack feet except for a single fused digit and die prenatally. Heterozygotes, in the presence of a recessive modifying allele, show loss of digits, frequently with fused metatarsal and metacarpal bones. |
Phenotype Images (1)
|
|
Polymorphisms
|
SNPs within 2kb(462 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (3 records)
Data Summary:
Assays (1)
Results (5)
Tissues (1)
Images (1)
Theiler Stages: 17
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
5 |
cDNA source data(67)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(70)
Genomic(2)
cDNA(67)
Primer pair(1)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:6607
Chai CK,
"Dactylaplasia in mice a two-locus model for development anomalies."
J Hered 1981 Jul-Aug;72(4):234-7
(Latest)
J:135784
Lo Iacono N et al.,
"Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects."
Development 2008 Apr;135(7):1377-88
|
All references(16)
|
Other
accession IDs
|
MGD-MRK-8791, MGI:94857
|
