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Aldh3a2 Gene Detail
 Symbol
Name
ID
Aldh3a2
aldehyde dehydrogenase family 3, subfamily A2
MGI:1353452

Nomenclature History
Synonyms Ahd-3, Ahd-3r, Ahd3, Ahd3-r, Aldh4, Aldh4-r, FALDH
Genetic Map
Chromosome 11
34.3 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 11)

Sequence Map
Chr11:61036919-61080966 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Aldh3a2 ± 2 cM)
Protein SuperFamily: aldehyde dehydrogenase
TreeFam: TF314264
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000005829 VEGA Gene Model | MGI Sequence Detail 44048 C57BL/6J ± Kb
transcript NM_007437 RefSeq | MGI Sequence Detail 3131 C57BL/6
polypeptide P47740 UniProt | EBI | MGI Sequence Detail 484 Not Applicable
For the selected sequences
All sequences(48)
Alleles
and
phenotypes 		All alleles(5) : Gene trapped(5)
Polymorphisms RFLP(2) SNPs within 2kb(405 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cellular aldehyde metabolic process, metabolic process...
Component endoplasmic reticulum, integral to membrane...
Function aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase [NAD(P)+] activity...
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (1)    Results (9)    Tissues (9)
Theiler Stages: 1,3,4,28
  Assay Type Assays   Results
      RT-PCR 1   9
cDNA source data(110)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(115) Genomic(1) cDNA(112) Primer pair(2)
Microarray probesets(2)
Pathways
putrescine degradation III
fatty acid α-oxidation
β-alanine biosynthesis I
L-lactaldehyde degradation (aerobic)
Other database
links
EC 1.2.1.3
Ensembl Gene Model ENSMUSG00000010025
DoTS DT.91405517, DT.94239148, DT.94293465
Consensus CDS Project CCDS24809.1
UniGene 398221
DFCI TC1573405
NIA Mouse Gene Index U032880
Entrez Gene 11671
VEGA Gene Model OTTMUSG00000005829
International Mouse Knockout Project Status Aldh3a2
Protein
domains
InterPro ID Description
IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
IPR015590 Aldehyde dehydrogenase
IPR016160 Aldehyde dehydrogenase, conserved site
IPR016161 Aldehyde/histidinol dehydrogenase
IPR016162 Aldehyde dehydrogenase, N-terminal
Graphical View of Protein Domain Structure
References
(Earliest) J:6570 Timms GP et al., "Genetics of aldehyde dehydrogenase isozymes in the mouse: evidence for multiple loci and localization of Ahd-2 on chromosome 19." Genetics 1981 Feb;97(2):327-36
(Latest) J:145577 Levi BP et al., "Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems." Blood 2009 Feb 19;113(8):1670-80
All references(26)
Other
accession IDs 		MGD-MRK-1207, MGD-MRK-1208, MGD-MRK-1214, MGD-MRK-1215, MGD-MRK-16379, MGD-MRK-16380, MGI:2144079, MGI:99597, MGI:99598
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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