Symbol
Name
ID
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Synonyms
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D930031B21Rik, Sur, SUR1
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(63)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(2)
Targeted, other(1)
| Homozygotes for targeted null mutations exhibit a transient neonatal hypoglycemia and a late-developing glucose intolerance. |
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Polymorphisms
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PCR(1)
SNPs within 2kb(612 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (4 records)
Data Summary:
Assays (3)
Results (10)
Tissues (9)
Images (2)
Theiler Stages: 19,21,22,23,25,26,28
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Assay Type |
Assays |
|
Results |
| |
RT-PCR |
2 |
|
9 |
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RNA in situ |
1 |
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1 |
cDNA source data(21)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(28)
Genomic(3)
cDNA(22)
Primer pair(3)
Microarray probesets(1)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR000388 |
Sulphonylurea receptor, N-terminal |
| IPR000844 |
Sulphonylurea receptor, type 1, N-terminal |
| IPR001140 |
ABC transporter, transmembrane domain |
| IPR003439 |
ABC transporter-like |
| IPR003593 |
ATPase, AAA+ type, core |
| IPR011527 |
ABC transporter, transmembrane domain, type 1 |
| IPR017871 |
ABC transporter, conserved site |
| IPR017940 |
ABC transporter integral membrane type 1 |
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References
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(Earliest)
J:39110
Aguilar-Bryan L et al.,
"Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion [see comments]"
Science 1995 Apr 21;268(5209):423-6
(Latest)
J:154622
Gier B et al.,
"Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress."
J Clin Invest 2009 Nov;119(11):3246-56
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All references(44)
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Other
accession IDs
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MGD-MRK-33673, MGI:105993, MGI:3036285
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Analysis Tools
MGI BioMart
