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Csnk1e Gene Detail
 Symbol
Name
ID
Csnk1e
casein kinase 1, epsilon
MGI:1351660


Nomenclature History
Synonyms CK1epsilon, CKI epsilon, CKIepsilon, KC1epsilon, tau
Genetic Map
Chromosome 15
cytoband E1
 
Mapping data( 5)
Sequence Map
Chr15:79248286-79274349 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat; hamster, golden    (Mammalian Orthology)
Protein SuperFamily: kinase-related transforming protein
TreeFam: TF300544
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000029589 VEGA Gene Model | MGI Sequence Detail 26064 C57BL/6J ± Kb
transcript NM_013767 RefSeq | MGI Sequence Detail 2760 -
polypeptide Q9JMK2 UniProt | EBI | MGI Sequence Detail 416 Not Applicable
For the selected sequences
All sequences(31)
Alleles
and
phenotypes
All alleles(55) : Targeted, knock-out(2) Targeted, other(4) Gene trapped(49)
Mice homozygous for a null allele exhibit disruptions in circadian rhythms.
Polymorphisms PCR(1) SNPs within 2kb(64 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process circadian rhythm, protein amino acid phosphorylation...
Component cytoplasm
Function ATP binding, kinase activity...
External Resources: FuncBase
Expression Literature Summary: (2 records)
cDNA source data(133)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(136) Genomic(1) cDNA(134) Primer pair(1)
Microarray probesets(3)
Other database
links
EC 2.7.11.1
Ensembl Gene Model ENSMUSG00000022433
DoTS DT.55100184, DT.55220996, DT.91391696
Consensus CDS Project CCDS27640.1
UniGene 30199
DFCI TC1575357, TC1615175, TC1685811
NIA Mouse Gene Index U036405
Entrez Gene 27373
VEGA Gene Model OTTMUSG00000029589
International Mouse Knockout Project Status Csnk1e
Protein
domains
InterPro ID Description
IPR000719 Protein kinase, catalytic domain
IPR008271 Serine/threonine-protein kinase, active site
IPR011009 Protein kinase-like domain
IPR017441 Protein kinase, ATP binding site
IPR017442 Serine/threonine-protein kinase-like domain
Graphical View of Protein Domain Structure
References
(Earliest) J:59123 Kusuda J et al., "cDNA cloning and chromosome mapping of the mouse casein kinase I epsilon gene (Csnk1e)." Cytogenet Cell Genet 1999;87(1-2):99-101
(Latest) J:150148 Etchegaray JP et al., "Casein kinase 1 delta regulates the pace of the mammalian circadian clock." Mol Cell Biol 2009 Jul;29(14):3853-66
All references(19)
Other
accession IDs
MGI:2145998, MGI:2146039, MGI:2146216

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/06/2010
MGI_4.32
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