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Poli Gene Detail
 Symbol
Name
ID
Poli
polymerase (DNA directed), iota
MGI:1347081

Nomenclature History
Synonyms Rad30b
Genetic Map
Chromosome 18
44.0 cM, cytoband E2
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr18:70668337-70689975 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Poli ± 2 cM)
Protein SuperFamily: DNA polymerase iota
TreeFam: TF324222
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000027289 VEGA Gene Model | MGI Sequence Detail 21639 C57BL/6J ± Kb
transcript NM_001136090 RefSeq | MGI Sequence Detail 2754 -
polypeptide Q6R3M4 UniProt | EBI | MGI Sequence Detail 717 Not Applicable
For the selected sequences
All sequences(32)
Alleles
and
phenotypes 		All alleles(13) : Gene trapped(12) Spontaneous(1)
Polymorphisms SNPs within 2kb(169 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(12)
Process DNA repair, DNA replication...
Component nucleus
Function damaged DNA binding, DNA binding...
External Resources: MouseFunc
Expression Literature Summary: (1 records)
cDNA source data(31)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(32) Genomic(1) cDNA(31)
Microarray probesets(2)
Other database
links
EC 2.7.7.7
Ensembl Gene Model ENSMUSG00000038425
DoTS DT.101135435, DT.101378258, DT.525648, DT.97395653, DT.99846709
UniGene 244352
DFCI TC1579175, TC1595391, TC1601735
NIA Mouse Gene Index U038542
Entrez Gene 26447
VEGA Gene Model OTTMUSG00000027289
International Mouse Knockout Project Status Poli
Protein
domains
InterPro ID Description
IPR001126 DNA-repair protein, UmuC-like
IPR017961 DNA polymerase, Y-family, little finger domain
IPR017963 DNA-repair protein, UmuC-like, N-terminal
Graphical View of Protein Domain Structure
References
(Earliest) J:57245 McDonald JP et al., "Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta." Genomics 1999 Aug 15;60(1):20-30
(Latest) J:117079 Dumstorf CA et al., "Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer." Proc Natl Acad Sci U S A 2006 Nov 28;103(48):18083-8
All references(16)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
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