Symbol
Name
ID
|
|
|
Synonyms
|
C230008H04Rik, JNK3, p493F12, Serk2
|
|
Genetic Map
|
|
Chromosome 5
|
cytoband E4
|
|
|
|
Mapping data(
2)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(46)
|
Alleles
and
phenotypes
|
All alleles(2) :
Targeted, knock-out(1)
Gene trapped(1)
| Mice homozygous for disruptions in this gene display a normal phenotype. They are resistant to kainic acid induced seizures and show increased resistance to MPTP induced Parkinson's disease. |
|
|
Polymorphisms
|
SNPs within 2kb(1646 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (9 records)
Data Summary:
Assays (1)
Results (9)
Tissues (3)
Images (5)
Theiler Stages: 23
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
1 |
|
9 |
cDNA source data(11)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(15)
Genomic(1)
cDNA(14)
Antibodies(1)
Microarray probesets(3)
|
Other database
links
|
| EC |
2.7.11.24 |
| Ensembl Gene Model |
ENSMUSG00000046709 |
| DoTS |
DT.101197129, DT.101391873, DT.101735368, DT.110648893, DT.529797, DT.94150758, DT.97362725 |
| Consensus CDS Project |
CCDS39185.1 |
| DFCI |
TC1576592, TC1590141, TC1590474, TC1597854, TC1599083, TC1599958 |
| NIA Mouse Gene Index |
U081043 |
| Entrez Gene |
26414 |
| VEGA Gene Model |
OTTMUSG00000016343 |
| International Mouse Knockout Project Status |
Mapk10 |
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000719 |
Protein kinase, catalytic domain |
| IPR002290 |
Serine/threonine-protein kinase domain |
| IPR003527 |
MAP kinase, conserved site |
| IPR008271 |
Serine/threonine-protein kinase, active site |
| IPR008351 |
JNK MAP kinase |
| IPR011009 |
Protein kinase-like domain |
| IPR017442 |
Serine/threonine-protein kinase-like domain |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:30685
Suzuki J et al.,
"Ontogeny of neuropsin mRNA expression in the mouse brain."
Neurosci Res 1995 Nov;23(4):345-51
(Latest)
J:154878
Abdelli S et al.,
"JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis."
Diabetologia 2009 Sep;52(9):1871-80
|
All references(36)
|
Other
accession IDs
|
MGD-MRK-36125, MGI:107554, MGI:2442453
|
Analysis Tools
MGI BioMart