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Mapk9 Gene Detail
 Symbol
Name
ID
Mapk9
mitogen-activated protein kinase 9
MGI:1346862


Nomenclature History
Synonyms JNK/SAPK alpha, JNK2, Prkm9
Genetic Map
Chromosome 11
cytoband B1.2
 
Mapping data( 3)
Sequence Map
Chr11:49660255-49699923 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: kinase-related transforming protein
TreeFam: TF105100
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000005569 VEGA Gene Model | MGI Sequence Detail 39669 C57BL/6J ± Kb
transcript NM_016961 RefSeq | MGI Sequence Detail 4682 -
polypeptide Q9WTU6 UniProt | EBI | MGI Sequence Detail 423 Not Applicable
For the selected sequences
All sequences(54)
Alleles
and
phenotypes
All alleles(9) : Targeted, knock-out(1) Targeted, other(2) Gene trapped(6)
Phenotype Images (4)  
Polymorphisms SNPs within 2kb(123 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(18)
Process induction of apoptosis in response to chemical stimulus, JNK cascade...
Component cytosolic part, nucleus...
Function ATP binding, JUN kinase activity...
External Resources: MouseFunc
Expression Literature Summary: (14 records)
Data Summary: Assays (9)    Results (33)    Tissues (9)    Images (10)
Theiler Stages: 20,21,24,26,28
  Assay Type Assays   Results
      Western blot 8   31
      Immunohistochemistry 1   2
cDNA source data(149)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(152) Genomic(1) cDNA(151) Antibodies(5)
Microarray probesets(4)
Other database
links
EC 2.7.11.24
Ensembl Gene Model ENSMUSG00000020366
DoTS DT.101164780, DT.110516248, DT.91570822, DT.94151506
UniGene 68933
DFCI TC1576918, TC1587317, TC1596768, TC1602296, TC1659476, TC1712050
NIA Mouse Gene Index U012540
Entrez Gene 26420
VEGA Gene Model OTTMUSG00000005569
International Mouse Knockout Project Status Mapk9
Protein
domains
InterPro ID Description
IPR000719 Protein kinase, catalytic domain
IPR002290 Serine/threonine-protein kinase domain
IPR003527 MAP kinase, conserved site
IPR008271 Serine/threonine-protein kinase, active site
IPR008351 JNK MAP kinase
IPR011009 Protein kinase-like domain
IPR017441 Protein kinase, ATP binding site
IPR017442 Serine/threonine-protein kinase-like domain
Graphical View of Protein Domain Structure
References
(Earliest) J:37627 Casanova E et al., "Identification of four splice variants of the mouse stress-activated protein kinase JNK/SAPK alpha-isoform." Neuroreport 1996 May 17;7(7):1320-4
(Latest) J:148191 Kodama Y et al., "Antiapoptotic effect of c-Jun N-terminal Kinase-1 through Mcl-1 stabilization in TNF-induced hepatocyte apoptosis." Gastroenterology 2009 Apr;136(4):1423-34
All references(99)
Other
accession IDs
MGI:1202396, MGI:2144306

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory