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Edar Gene Detail
 Symbol
Name
ID
Edar
ectodysplasin-A receptor
MGI:1343498


Nomenclature History
Genetic Map
Chromosome 10
29.0 cM, cytoband B3
Detailed Genetic Map ± 1 cM
 
Mapping data( 13)

Sequence Map
Chr10:58063537-58138402 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Edar ± 2 cM)
TreeFam: TF331385
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000025045 VEGA Gene Model | MGI Sequence Detail 74866 C57BL/6J ± Kb
transcript NM_010100 RefSeq | MGI Sequence Detail 3697 C57BL/6
polypeptide Q9R187 UniProt | EBI | MGI Sequence Detail 448 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes
All alleles(9) : Targeted, other(2) Transgenic(2) Spontaneous(4) Chemically induced(1)
Mutations in this gene produce abnormalities of the hair,teeth and some exocrine glands.
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (2)  
Polymorphisms RFLP(1) SNPs within 2kb(489 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(17)
Process apoptosis, cell differentiation...
Component apical part of cell, integral to membrane...
Function protein binding, receptor activity...
External Resources: MouseFunc
Expression Literature Summary: (32 records)
Data Summary: Assays (10)    Results (75)    Tissues (48)    Images (47)
Theiler Stages: 16,17,18,19,20,21,22,23,24,25,28
  Assay Type Assays   Results
      RNA in situ 10   75
cDNA source data(8)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(26) Genomic(15) cDNA(8) Other(3)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000003227
DoTS DT.55255277
UniGene 174523
DFCI TC1592183, TC1627123
NIA Mouse Gene Index U031806
Entrez Gene 13608
VEGA Gene Model OTTMUSG00000025045
International Mouse Knockout Project Status Edar
Protein
domains
InterPro ID Description
IPR000488 Death
IPR001368 TNFR/CD27/30/40/95 cysteine-rich region
IPR011029 DEATH-like
Graphical View of Protein Domain Structure
References
(Earliest) J:18293 Phillips RJS, "New mutant" Mouse News Lett 1960;23():29-30
(Latest) J:152818 Melnick M et al., "Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm." BMC Dev Biol 2009;9():32
All references(68)
Other
accession IDs
MGD-MRK-8853, MGI:94898

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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