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Eya4 Gene Detail
 Symbol
Name
ID
Eya4
eyes absent 4 homolog (Drosophila)
MGI:1337104


Nomenclature History
Synonyms B130023L16Rik
Genetic Map
Chromosome 10
18.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr10:22823974-23069701 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Eya4 ± 2 cM)
Protein SuperFamily: eyes absent protein
TreeFam: TF319337
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000010461 Ensembl Gene Model | MGI Sequence Detail 245728 C57BL/6J ± Kb
transcript NM_010167 RefSeq | MGI Sequence Detail 4099 C57BL/6
polypeptide Q9Z191 UniProt | EBI | MGI Sequence Detail 616 Not Applicable
For the selected sequences
All sequences(24)
Alleles
and
phenotypes
All alleles(1) : Targeted, knock-out(1)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)   Phenotype Images (5)  
Polymorphisms RFLP(1) SNPs within 2kb(1824 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(16)
Process chromatin modification, DNA repair...
Component cytoplasm, nucleus...
Function catalytic activity, hydrolase activity...
External Resources: MouseFunc
Expression Literature Summary: (2 records)
Data Summary: Assays (3)    Results (59)    Tissues (41)
Theiler Stages: 15,17,19,20,28
  Assay Type Assays   Results
      RNA in situ 2   51
      Northern blot 1   8
cDNA source data(9)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(2)
Other database
links
EC 3.1.3.48
Ensembl Gene Model ENSMUSG00000010461
DoTS DT.101152020, DT.40180318, DT.94227852
DFCI TC1586215, TC1592138, TC1647190
NIA Mouse Gene Index U031606
Entrez Gene 14051
International Mouse Knockout Project Status Eya4
Protein
domains
InterPro ID Description
IPR005834 Haloacid dehalogenase-like hydrolase
IPR006545 EYA
Graphical View of Protein Domain Structure
References
(Earliest) J:52368 Borsani G et al., "EYA4, a novel vertebrate gene related to Drosophila eyes absent." Hum Mol Genet 1999 Jan;8(1):11-23
(Latest) J:131873 Depreux FF et al., "Eya4-deficient mice are a model for heritable otitis media." J Clin Invest 2008 Feb;118(2):651-8
All references(5)
Other
accession IDs
MGI:2442271

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory